Cancer and Your Genes

NY Times Article on Sunscreens for Those Interested in Prevention of Melanoma and Other Skin Cancers

If you have a family history of melanoma or are just interested in doing everything you can to prevent skin cancer, you may be interested in this article by Tara Parker-Pope at the NY Times.

Tony Snow, Former Bush Press Secretary, Dies at 53: A Reminder About Familial Colon Cancer and Opportunities for Prevention

Tony Snow, the conservative writer, commentator, and former Bush administration Press Secretary, died on the morning of July 12 at the age of 53 of colorectal cancer. 

It's worth mentioning that Mr. Snow had a family history of colon cancer, as his mother apparently died of the disease when he was 17 years old.  As Mr. Snow has publicly acknowledged a diagnosis of ulcerative colitis (UC), it seems most likely that the cancer in his family is related to UC, rather than to what are arguably the two most important hereditary cancer predisposition syndromes for colon cancer, Lynch syndrome (aka hereditary non-polyposis colorectal cancer or HNPCC) and familial adenomatous polyposis (FAP).

The lifetime risk for colon cancer in individuals at average risk in the United States is about 5 percent.  Nine out of ten cases occur after the age of 50.  Individuals with ulcerative colitis have a ~3- to 12-fold elevated risk of developing colon cancer depending on the extent of colon involvement and the length of time the disease has been present.  Ulcerative colitis risk is influenced by genetics, but the inheritance is complex, without major deterministic susceptibility genes like those for FAP (APC) and Lynch syndrome (MLH1, MSH2, MSH6, PMS2). 

Mr. Snow's death is an opportunity to remind folks that colon cancer, in general, is a highly preventable disease.  Stay tuned to future posts for more details.

Brewing Turf War Between Breast Surgeons and Plastic Surgeons Over Breast Reconstruction

The Wall Street Journal Health Blog has an interesting story on a brewing turf war between breast surgeons and plastic surgeons over breast reconstruction procedures.

Some women with breast cancer - including some with BRCA1 or BRCA2 mutations undergoing bilateral mastectomy - decide to have breast reconstruction performed.  This procedure has generally been performed by a plastic surgeon in a separate procedure from the mastectomy itself.  Now, as noted by the WSJ, a growing number of breast surgeons (without plastics training) are learning the breast reconstruction procedures and beginning to offer it at the same time as the mastectomy itself. 

Undoubtedly, this will lead to some turf wars.  If you are shopping around for a breast reconstruction surgeon, the most important question to ask is how many breast reconstruction procedures have they done...

Poetry and Art as Outlets for Cancer Patients

Tara Parker-Pope at the Well blog (NY Times) has an interesting post on poetry as an expressive outlet for cancer patients. 

Other forms of art can also be helpful (see here):

• Confronting Cancer Through Art
• Art for Recovery
• Joan Bowman
• The Art Therapy Blog
• Strength from Unity
• Arts in Medicine Program